A new cell type that could stop allergies before they begin has been discovered by researchers at The Centre for Personalised Immunology.
In Australia, 1 in 5 people suffer from allergic conditions and this finding gives hope to people who live with a range of allergic conditions including asthma, eczema and life-threatening anaphylaxis.
“In allergic individuals, the immune system thinks that harmless particles like peanuts, dust or common allergens are a threat, and then mounts an immune response which manifests itself from mild localised symptoms like a runny nose during hay fever season, to very aggressive systemic inflammation like anaphylaxis.” said lead researcher and PhD scholar Pablo F Canete, in the ANU press release.
The cell discovered in this research prevent immune overactivity by secreting a signal to stop production of the antibody, Immunoglobulin E (IgE). It is already known that this antibody (IgE) is the key trigger of allergic reactions.