Dr Klaus Schwarz

University of Ulm | Germany

Klaus is a Paediatrician and Immunologist with 25 years of experience and expertise in identification of genetic defects leading to SCID and related immunodeficiencies. Highlights include discoveries that RAG1 or RAG2 deficiency in humans leads to SCID (Science, 1996, 264 citations), DNA Ligase IV is essential for human precursor lymphocytes (Mol Cell 1998, 207 citations), and characterization of the enzymatic activity of ARTEMIS (Cell, 2002, 537 citations). More recently his group discovered that mutations in adenylate kinase 2 underlie reticular dysgenesis, the most severe form of primary immunodeficiency (Nature Gen 2009, 54 citations).